Cluster (n)

MIRU-VNTR profile¹

Gene

Result of LPA

Number of strains

rpoB

katG

mabA inhA

wt²

mutation

wt

mutation

wt

mutation

Cluster 1 (6)

264333233531436253213422

7

H526D

-³

S315T

+⁴

-

MDR

4

7

Unknown

-

S315T

+

-

MDR

2

Cluster 2 (27)

264333233431436253213422

8

S531L

-

S315T

+

-

MDR

5

7

H526Y

-

S315T

+

-

MDR

5

7

H526Y

-

S315T

2

T8C

MDR

4

7

H526D

-

S315T

2

T8C

MDR

3

3/4

D516V

-

S315T

2

T8C

MDR

3

3/4/7

Unknown

-

S315T

2

T8C

MDR

1

7

H526D

-

S315T

+

-

MDR

1

7

Unknown

-

S315T

2

T8C

MDR

1

7

Unknown

-

S315T

2

T8A

MDR

1

8

S531L

-

S315T

2

T8A

MDR

1

+

-

-

S315T

+

-

INHR

1

+

-

-

S315T

2

T8C

INHR

1

Cluster 3 (3)

254333233431436253213422

7

Unknown

-

S315T

+

-

MDR

2

3/4

D516V

-

S315T

+

-

MDR

1

Cluster 4 (3)

244333233431436253213422

7

Unknown

-

S315T

+

-

MDR

2

1/7

Unknown

-

S315T

+

-

MDR

1

Cluster 5 (6)

274333233431436253213422

8

S531L

-

S315T

+

-

MDR

3

7

Unknown

-

S315T

+

-

MDR

1

3/4

Unknown

-

S315T

+

-

MDR

1

7

H526Y

-

S315T

+

-

MDR

1

Cluster 6 (2)

264333233431426253213422

7

H526Y

-

S315T

2

T8C

MDR

2

Cluster 7 (3)

263333233431436253213422

3/4

D516V

-

S315T

+

-

MDR

2

8

S531L

-

S315T

+

-

MDR

1

Cluster 8 (2)

274333133431436253213422

3/4

D516V

-

S315T

+

-

MDR

2

Cluster 9 (4)

264333133431436253213422

3/4

D516V

-

S315T

+

-

MDR

4